DRUG BINDING INTERFACES MAPPED TO 'PROTEIN ARGONAUTE-2'
List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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Only hits with patterns containing 3-12 residues
DrReposER ID
PDB
Ligand
Organism
Macromolecule
Pfam
Res.
Interface
HETATM
4F3T_A_IPHA901
4f3t
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoN)PF02171(Piwi)PF08699(PAZ)PF16486(ArgoL1)PF16487(ArgoL2)PF16488(ArgoMid)
4
PHE A 587VAL A 591ALA A 620PHE A 653
IPH A 901
4F3T_A_IPHA902
4f3t
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoN)PF02171(Piwi)PF08699(PAZ)PF16486(ArgoL1)PF16487(ArgoL2)PF16488(ArgoMid)
6
LEU A 650TYR A 654LYS A 660LEU A 694GLU A 695TYR A 698
IPH A 902
4OLA_A_IPHA901
4ola
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL1)PF02171(ArgoMid)PF08699(ArgoL2)PF16486(ArgoN)PF16487(PAZ)PF16488(Piwi)
5
TYR A 654LYS A 660LEU A 694GLU A 695TYR A 698
IPH A 901
4OLB_A_TRPA901
4olb
TRP
DB00150(L-Tryptophan)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
3
VAL A 591ALA A 620PHE A 653
TRP A 901
4OLB_A_TRPA902
4olb
TRP
DB00150(L-Tryptophan)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
5
TYR A 654LYS A 660LEU A 694GLU A 695TYR A 698
TRP A 902
4W5N_A_IPHA901
4w5n
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
3
VAL A 591ALA A 620PHE A 653
IPH A 901
4W5N_A_IPHA902
4w5n
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
6
LEU A 650ILE A 651LYS A 660LEU A 694GLU A 695TYR A 698
IPH A 902
4W5N_A_IPHA903
4w5n
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
4
TYR A 174THR A 183GLY A 201LEU A 382
IPH A 903
4W5O_A_IPHA904
4w5o
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
7
ARG A 688CYS A 691ILE A 692GLN A 699PRO A 700ILE A 702ASP A 771
IPH A 904
4W5O_A_IPHA905
4w5o
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
4
TYR A 654LYS A 660GLU A 695TYR A 698
IPH A 905
4W5O_A_IPHA906
4w5o
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
5
PHE A 587PRO A 590VAL A 591ALA A 620PHE A 653
IPH A 906
4W5O_A_IPHA907
4w5o
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
5
ALA A 543LYS A 570THR A 852THR A 855TYR A 857
IPH A 907
4W5Q_A_IPHA902
4w5q
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
6
ARG A 688CYS A 691ILE A 692GLN A 699ILE A 702ASP A 771
IPH A 902
4W5Q_A_IPHA903
4w5q
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
5
TYR A 654LYS A 660PRO A 661LEU A 694TYR A 698
IPH A 903
4W5Q_A_IPHA904
4w5q
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
4
PHE A 587VAL A 591ALA A 620PHE A 653
IPH A 904
4W5Q_A_IPHA905
4w5q
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
6
ASP A 537ALA A 543LYS A 570THR A 852THR A 855TYR A 857
IPH A 905
4W5R_A_IPHA903
4w5r
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
4
TYR A 654LYS A 660GLU A 695TYR A 698
IPH A 903
4W5R_A_IPHA904
4w5r
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
4
PHE A 587VAL A 591ALA A 620PHE A 653
IPH A 904
4W5R_A_IPHA905
4w5r
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
6
ASP A 537ALA A 543LYS A 570THR A 852THR A 855TYR A 857
IPH A 905
4W5T_A_IPHA902
4w5t
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
6
ARG A 688CYS A 691ILE A 692GLN A 699ILE A 702ASP A 771
IPH A 902
4W5T_A_IPHA903
4w5t
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
5
TYR A 654LYS A 660PRO A 661GLU A 695TYR A 698
IPH A 903
4W5T_A_IPHA904
4w5t
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
4
PHE A 587VAL A 591ALA A 620PHE A 653
IPH A 904
4W5T_A_IPHA905
4w5t
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
6
ASP A 537ALA A 543LYS A 570THR A 852THR A 855TYR A 857
IPH A 905
4Z4C_A_IPHA903
4z4c
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
6
ARG A 688CYS A 691ILE A 692GLN A 699ILE A 702ASP A 771
IPH A 903
4Z4C_A_IPHA904
4z4c
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
6
TYR A 654LYS A 660PRO A 661LEU A 694GLU A 695TYR A 698
IPH A 904
4Z4C_A_IPHA905
4z4c
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
5
PHE A 587PRO A 590VAL A 591ALA A 620PHE A 653
IPH A 905
4Z4C_A_IPHA906
4z4c
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
6
ASP A 537ALA A 543LYS A 570THR A 852THR A 855TYR A 857
IPH A 906
4Z4D_A_IPHA902
4z4d
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
6
ARG A 688CYS A 691ILE A 692GLN A 699ILE A 702ASP A 771
IPH A 902
4Z4D_A_IPHA903
4z4d
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
5
TYR A 654LYS A 660LEU A 694GLU A 695TYR A 698
IPH A 903
4Z4D_A_IPHA904
4z4d
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
5
PHE A 587PRO A 590VAL A 591ALA A 620PHE A 653
IPH A 904
4Z4D_A_IPHA905
4z4d
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
5
ALA A 543LYS A 570THR A 852THR A 855TYR A 857
IPH A 905
4Z4E_A_IPHA904
4z4e
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
7
ARG A 688CYS A 691ILE A 692GLN A 699PRO A 700ILE A 702ASP A 771
IPH A 904
4Z4E_A_IPHA905
4z4e
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
4
TYR A 654LYS A 660GLU A 695TYR A 698
IPH A 905
4Z4E_A_IPHA906
4z4e
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
5
PHE A 587PRO A 590VAL A 591ALA A 620PHE A 653
IPH A 906
4Z4E_A_IPHA907
4z4e
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
5
ALA A 543LYS A 570THR A 852THR A 855TYR A 857
IPH A 907
4Z4F_A_IPHA902
4z4f
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
7
LEU A 650TYR A 654LYS A 660PRO A 661LEU A 694GLU A 695TYR A 698
IPH A 902
4Z4F_A_IPHA903
4z4f
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
4
VAL A 591ALA A 620PHE A 653THR A 657
IPH A 903
4Z4F_A_IPHA904
4z4f
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
6
ASP A 537ALA A 543LYS A 570THR A 852THR A 855TYR A 857
IPH A 904
4Z4G_A_IPHA902
4z4g
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL1)PF02171(ArgoMid)PF08699(ArgoL2)PF16486(ArgoN)PF16487(PAZ)PF16488(Piwi)
7
ARG A 688CYS A 691ILE A 692GLN A 699PRO A 700ILE A 702ASP A 771
IPH A 902
4Z4G_A_IPHA903
4z4g
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL1)PF02171(ArgoMid)PF08699(ArgoL2)PF16486(ArgoN)PF16487(PAZ)PF16488(Piwi)
6
LEU A 650TYR A 654LYS A 660PRO A 661GLU A 695TYR A 698
IPH A 903
4Z4G_A_IPHA904
4z4g
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL1)PF02171(ArgoMid)PF08699(ArgoL2)PF16486(ArgoN)PF16487(PAZ)PF16488(Piwi)
4
PHE A 587VAL A 591ALA A 620PHE A 653
IPH A 904
4Z4G_A_IPHA905
4z4g
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL1)PF02171(ArgoMid)PF08699(ArgoL2)PF16486(ArgoN)PF16487(PAZ)PF16488(Piwi)
5
ASP A 537ALA A 543THR A 852THR A 855TYR A 857
IPH A 905
4Z4H_A_IPHA902
4z4h
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoN)PF02171(Piwi)PF08699(PAZ)PF16486(ArgoL1)PF16487(ArgoL2)PF16488(ArgoMid)
5
TYR A 654LYS A 660LEU A 694GLU A 695TYR A 698
IPH A 902
4Z4H_A_IPHA903
4z4h
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoN)PF02171(Piwi)PF08699(PAZ)PF16486(ArgoL1)PF16487(ArgoL2)PF16488(ArgoMid)
4
VAL A 591ALA A 620PHE A 653THR A 657
IPH A 903
4Z4H_A_IPHA904
4z4h
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoN)PF02171(Piwi)PF08699(PAZ)PF16486(ArgoL1)PF16487(ArgoL2)PF16488(ArgoMid)
5
ARG A 688GLN A 699PRO A 700ILE A 702ASP A 771
IPH A 904
4Z4H_A_IPHA905
4z4h
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoN)PF02171(Piwi)PF08699(PAZ)PF16486(ArgoL1)PF16487(ArgoL2)PF16488(ArgoMid)
5
ASP A 537ALA A 543LYS A 570THR A 855TYR A 857
IPH A 905
4Z4I_A_IPHA902
4z4i
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
4
TYR A 654LYS A 660GLU A 695TYR A 698
IPH A 902
4Z4I_A_IPHA903
4z4i
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
3
VAL A 591ALA A 620PHE A 653
IPH A 903
4Z4I_A_IPHA904
4z4i
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
6
ASP A 537ALA A 543LYS A 570THR A 852THR A 855TYR A 857
IPH A 904
5JS1_A_IPHA901
5js1
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
5
TYR A 654LYS A 660LEU A 694GLU A 695TYR A 698
IPH A 901
5JS1_A_IPHA902
5js1
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
3
VAL A 591ALA A 620PHE A 653
IPH A 902
5KI6_A_IPHA901
5ki6
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
5
LEU A 650TYR A 654LYS A 660LEU A 694TYR A 698
IPH A 901
5KI6_A_IPHA902
5ki6
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
4
PHE A 587VAL A 591ALA A 620PHE A 653
IPH A 902
5KI6_A_IPHA903
5ki6
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL2)PF02171(ArgoL1)PF08699(Piwi)PF16486(PAZ)PF16487(ArgoMid)PF16488(ArgoN)
5
ARG A 688CYS A 691GLN A 699PRO A 700ILE A 702
IPH A 903
5T7B_A_IPHA901
5t7b
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL1)PF02171(ArgoMid)PF08699(ArgoL2)PF16486(ArgoN)PF16487(PAZ)PF16488(Piwi)
6
PHE A 587PRO A 590VAL A 591ALA A 620PHE A 653THR A 657
IPH A 901
5T7B_A_IPHA902
5t7b
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoL1)PF02171(ArgoMid)PF08699(ArgoL2)PF16486(ArgoN)PF16487(PAZ)PF16488(Piwi)
7
LEU A 650TYR A 654LYS A 660PRO A 661LEU A 694GLU A 695TYR A 698
IPH A 902
5WEA_A_IPHA901
5wea
IPH
DB03255(Phenol)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(PAZ)PF02171(ArgoN)PF08699(ArgoMid)PF16486(ArgoL2)PF16487(Piwi)PF16488(ArgoL1)
5
LEU A 650TYR A 654LYS A 660LEU A 694GLU A 695
IPH A 901
6CBD_A_TRPA901
6cbd
TRP
DB00150(L-Tryptophan)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoN)PF02171(Piwi)PF08699(PAZ)PF16486(ArgoL1)PF16487(ArgoL2)PF16488(ArgoMid)
5
TYR A 654LYS A 660LEU A 694GLU A 695TYR A 698
TRP A 901
6CBD_A_TRPA902
6cbd
TRP
DB00150(L-Tryptophan)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoN)PF02171(Piwi)PF08699(PAZ)PF16486(ArgoL1)PF16487(ArgoL2)PF16488(ArgoMid)
4
VAL A 591ALA A 620PHE A 653PHE A 659
TRP A 902
6CBD_A_TRPA903
6cbd
TRP
DB00150(L-Tryptophan)
Homo sapiens
PROTEIN ARGONAUTE-2
PF02170(ArgoN)PF02171(Piwi)PF08699(PAZ)PF16486(ArgoL1)PF16487(ArgoL2)PF16488(ArgoMid)
6
ARG A 688CYS A 691ILE A 692GLN A 699ILE A 702ASP A 771
TRP A 903
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